Your PCOS Doesn’t Look Like Anyone Else’s. Your Treatment Shouldn’t Either.
PCOS shows up differently for every woman — weight changes, acne, hair loss, unwanted facial hair, irregular cycles. Most doctors treat one symptom at a time. Oana’s licensed physicians may recommend personalized combinations to address both the metabolic and hormonal sides of PCOS, if appropriate for you.
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PCOS Is More Than Weight
Polycystic Ovary Syndrome affects an estimated 8–13% of women of reproductive age, according to the World Health Organization — and it shows up in dozens of different ways. Some women struggle with stubborn weight gain. Others get hormonal acne that won’t respond to anything. Many deal with unwanted facial hair, hair thinning, irregular periods, fatigue, or all of the above.
Many providers focus on a single symptom at a time. Oana’s licensed physicians review your full symptom history during a health intake and may recommend a treatment approach that addresses multiple symptoms together, if clinically appropriate for you.
What PCOS Symptoms Are You Dealing With?
PCOS rarely presents as just one thing. Click any symptom you’re experiencing — the assessment will match you to treatment options for your specific combination.
Metabolic & Cycle Support
Cravings, fatigue, irregular cycles, and blood sugar patterns can be tied to insulin resistance in PCOS.
Metformin · MetSpiroHormonal Acne
Cystic breakouts along the jawline and chin. Doesn’t respond to typical skincare. Worsens before your period.
Spironolactone · Combination PlansUnwanted Facial Hair
Dark, coarse hair on the chin, upper lip, jawline. Caused by elevated androgens. Waxing doesn’t address the cause.
Eflornithine Cream · SpironolactoneHair Loss & Thinning
Diffuse thinning along the top of the scalp. Widening part. Usually androgen-driven in PCOS.
Oral Minoxidil · SpironolactoneIrregular Periods
Cycles longer than 35 days, skipped periods, or unpredictable bleeding. A core PCOS symptom tied to hormonal imbalance.
Metformin · MetSpiroAll of the Above
Most women with PCOS have multiple symptoms at once. The right approach treats the root cause AND each specific symptom — together.
Personalized Combination PlansWhy Most PCOS Treatment Falls Short
You see your doctor. They run a few labs. They tell you to lose weight, take birth control, or try a topical cream. Six months later, nothing has changed — and you’re left wondering if this is just your life now.
Insulin Resistance Is the Root
Many women with PCOS experience insulin resistance — research suggests it may affect a majority of women with PCOS, even at a normal weight. Excess insulin may signal the ovaries to produce more androgens, which are associated with several PCOS symptoms including weight changes, acne, unwanted hair growth, hair thinning, and irregular cycles.
Single-Symptom Treatment Doesn’t Work
A topical cream for acne won’t fix the androgens causing the breakouts. A pill for hair loss won’t address the underlying hormonal imbalance. Treating PCOS one symptom at a time is treating the smoke while ignoring the fire.
Personalized Combinations Work
PCOS shows up differently for every woman. Effective treatment often combines therapies — metformin for insulin resistance combined with spironolactone for hormonal symptoms, or eflornithine for unwanted facial hair, depending on your individual symptom profile and what your physician recommends.
Focused Care, Not Generalist Care
Oana’s licensed physicians focus on hormonal health and PCOS care. They review your full symptom pattern and may recommend treatment combinations as your symptoms evolve, if appropriate. This is ongoing physician-supervised care.
The Full Suite of PCOS Treatments — All Through One Platform
Many women’s treatment plans include more than one medication. Your assessment will match you to options that fit your symptom pattern. A licensed physician will determine the appropriate plan during your health intake review.
Metformin ER
The foundation of PCOS treatment. Improves insulin sensitivity, helps regulate periods, lowers androgens. ER formula for fewer GI side effects. The most affordable starting point.
MetSpiro Combo
Metformin + Spironolactone in one plan. Addresses both the metabolic AND hormonal sides of PCOS at the same time. Our most common prescription.
Spironolactone
Anti-androgen treatment for hormonal acne, unwanted facial hair, and hair thinning. Often combined with metformin for broader coverage.
Eflornithine Cream
Topical prescription cream that slows unwanted facial hair growth at the follicle level. The same active ingredient as the brand-name alternative.
Oral Minoxidil
Pill-form treatment for PCOS-related hair thinning and shedding. Often more effective than topical for diffuse thinning.
The right approach depends on your specific symptom pattern. The 60-second assessment matches you to potential treatment options. A licensed physician reviews your health intake and determines the appropriate plan if treatment is right for you.
Treatment Combinations Your Physician May Consider
PCOS rarely has just one cause or one symptom. Some women benefit from a treatment approach that addresses multiple aspects of PCOS at once. Here are some combinations a licensed physician may consider, depending on your individual symptom profile:
Metformin + Spironolactone
May be considered for women with both metabolic and hormonal PCOS symptoms. Metformin is associated with insulin sensitivity. Spironolactone may help with androgen-related symptoms. Both medications are FDA-approved and used off-label for PCOS. If prescribed.
Your assessment will match you to potential options. A licensed physician determines the appropriate treatment for you based on your full health intake, if prescribed.
What Some of Our Patients Have Shared
“I came in for help with PCOS symptoms and ended up on metformin and spironolactone. After several months, I’ve noticed improvements in how I feel overall. I had no idea PCOS could be approached this way.”
Individual results may vary. Testimonial reflects the experience of one Oana patient and is not necessarily typical.
“My PCOS symptoms were mostly around facial hair. My Oana physician prescribed spironolactone and eflornithine cream. I’ve noticed a meaningful difference in my symptoms over time.”
Individual results may vary. Testimonial reflects the experience of one Oana patient and is not necessarily typical.
“I’d spent years trying different things for my PCOS without much success. My Oana physician took a comprehensive look at my symptoms and we discussed treatment options together. I appreciate having found a more thorough approach to my care.”
Individual results may vary. Testimonial reflects the experience of one Oana patient and is not necessarily typical.
All testimonials reflect the individual experiences of actual Oana patients with their consent. Individual results vary and are not guaranteed. Testimonials are not intended to represent or guarantee that anyone will achieve the same or similar results. Treatment decisions are made by a licensed physician based on your individual health intake.
How Oana Works
Take the 60-Second Assessment
Answer a few questions about your PCOS symptoms and what you’ve tried. We’ll match you to potential treatment options based on your answers — your physician will determine what’s appropriate for you.
Physician Reviews Your Case
A licensed physician with experience in hormonal health reviews your full health intake and determines the appropriate treatment, if any, within 1–2 business days. The physician makes all treatment decisions.
Treatment Ships Free
If prescribed, your medications arrive at your door with free shipping. Refills, ongoing physician support, and adjustments to your plan as your symptoms evolve.
PCOS Treatment Has More Options Than Many Women Realize
Many women come to Oana already taking one medication for PCOS, often without realizing that combination approaches exist or that other options may be appropriate. The right approach depends on your specific symptom pattern — and that’s a conversation between you and a licensed physician.
Questions worth asking your physician about your PCOS treatment:
- Are my current treatments addressing the underlying metabolic factors, or only one symptom?
- Could a combination of treatments be appropriate for my symptom pattern?
- What FDA-approved options are available for my specific symptoms?
- If I’m not seeing improvement, what alternatives might be considered?
- How are decisions made about whether compounded medications are appropriate when FDA-approved options exist?
Frequently Asked Questions
It’s a 60-second questionnaire about your PCOS symptoms, what you’ve tried, and what matters most to you in treatment. Based on your answers, we match you to potential treatment options. A licensed physician then reviews your health intake and determines the appropriate treatment for you, if any. The physician makes all treatment decisions — the assessment is a matching tool, not a prescription.
PCOS rarely has just one cause or one symptom. For many women, insulin resistance is associated with the production of androgens, which can contribute to several PCOS symptoms. A treatment approach that addresses both the metabolic and the hormonal sides of PCOS may be considered by a physician. Whether more than one medication is right for you depends on your individual health and is a decision made by a licensed physician based on your health intake.
Treatments range from $17/month (spironolactone alone) to $285/month for the most comprehensive combination. Most women’s plans fall in the $32–$185/month range depending on their symptoms. All treatments include free shipping and a one-time $20 doctor visit. No insurance required. FSA/HSA eligible. All prescriptions, including compounded medications, require physician evaluation and approval. Compounded medications are not FDA-approved. The $20 doctor visit fee covers the physician’s review of your health intake.
Yes. Your Oana physician can adjust your plan at any time. Many women start with one or two treatments and add others as their needs change. PCOS is a long-term condition — your treatment should evolve with you.
That’s exactly what the assessment is for. Most women aren’t sure whether their symptoms are PCOS, hormonal, metabolic, or something else. The questionnaire helps narrow it down, and the physician review confirms whether PCOS treatment is appropriate for you. If it’s not, they’ll tell you.
No. Many women experience PCOS symptoms for years before getting an official diagnosis. The Oana physicians can evaluate your symptoms during the health intake and prescribe treatment if appropriate. If you do have a formal diagnosis, share it during your intake — it helps with personalization.
It varies depending on the medication and your individual response. Many medications take weeks to months to show effects, and some symptoms may improve before others. Your physician can discuss expected timelines based on your specific treatment plan during your health intake review. Individual results vary.
Stop Treating PCOS One Symptom at a Time
Take the 60-second assessment and get matched to treatment options. A licensed physician with experience in hormonal health will review your health intake and determine the appropriate treatment, if prescribed.
Take the 60-Second AssessmentImportant Safety and Compliance Information
The information on this page is for educational purposes only and is not medical advice. It is not a substitute for consultation with a qualified healthcare provider.
About FDA Approval Status:
- Metformin is FDA-approved for the treatment of type 2 diabetes. Use for PCOS is off-label and based on physician clinical judgment.
- Spironolactone is FDA-approved as a diuretic and for treatment of certain conditions. Use for PCOS-related symptoms is off-label.
- Eflornithine cream at 13.9% (brand-name Vaniqa) is FDA-approved for the reduction of unwanted facial hair in women. The eflornithine 12% cream dispensed through Oana is a compounded preparation and is not FDA-approved.
- Oral minoxidil is FDA-approved for hypertension. Use for hair loss is off-label.
Treatment Decisions:
Treatment decisions, including whether to prescribe any medication, are made solely by licensed physicians based on a review of your individual health intake. The Oana platform matches users to potential treatment options based on assessment answers but does not prescribe medications. No prescription is guaranteed.
Individual Results:
Individual results vary. Testimonials and patient experiences shared on this page reflect individual outcomes and are not guaranteed or representative of typical results.
Telehealth Disclosure:
Oana-affiliated medical practices are independently owned and operated by licensed physicians who provide services using the Oana telehealth platform. Oana is not a pharmacy and is not financially affiliated with any pharmacy or pharmaceutical company.