Metformin ER
First-line for insulin resistance — the metabolic engine behind most PCOS symptoms.
Start a metformin visitOne intake helps your care team review multiple Rx options for insulin resistance, acne, unwanted hair, and skin texture — only what is appropriate for your symptoms.




None of these are prescribed by default. The intake decides which fit your symptom pattern.
First-line for insulin resistance — the metabolic engine behind most PCOS symptoms.
Start a metformin visitAnti-androgen that may help with hormonal acne, oil, and androgenic hair regrowth.
Start a spironolactone visitA topical cream that slows new facial hair growth at the follicle. Same active as Vaniqa.
Start an eflornithine visitPrescription retinoid that may help acne, texture, post-acne marks, and tone.
Start a tretinoin visitThe cluster of symptoms women with PCOS describe — insulin resistance, hormonal acne, unwanted hair, cycle irregularity — connects through overlapping pathways. The plan that helps tends to address several at once, when appropriate.
Tell us where the PCOS is loudest. A licensed provider matches the plan to your case — only what is appropriate.
Share your symptoms, history, and any labs you have. Takes about 5 minutes from your phone.
A licensed provider reviews your case and prescribes the combination — or single product — that is appropriate. Some patients only need one.
Your prescriptions ship free in plain packaging. Refills are automatic. Adjust the plan over time through your care team.
Reviews from women using a multi-product PCOS care plan with Oana.
"I had been bouncing between a dermatologist for the acne and my PCP for the metformin. Having one place that sees the whole picture is night and day."
"My provider didn't prescribe everything — she said I only needed the metformin for now. The fact that she said no to something is what made me trust her."
Start a short online visit. A licensed provider reviews your full PCOS picture and prescribes only what is appropriate — sometimes one product, sometimes a combination.
View PCOS treatments*Prescription treatment if appropriate. PCOS care plans are individualized — products listed may or may not be prescribed depending on your provider's review of your symptoms, history, and any labs. Spironolactone, metformin, and tretinoin should not be used during pregnancy. Eflornithine slows new hair growth and does not remove existing hair. The decision to prescribe is at the discretion of your Oana-affiliated provider. Not all patients are candidates. Individual results vary.