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If you’ve been dealing with hormonal breakouts—especially around your jawline, chin, or lower cheeks—you’ve probably heard about spironolactone as a treatment option. But should you take it orally, or apply it topically?
Both forms can be effective for acne—but they work differently and are suited for different needs.
In this post, we’ll break down topical vs oral spironolactone for acne, and help you decide which one may be right for your skin.
👉 Oana Health offers both options, delivered straight to your door:
• Topical Spironolactone
• Oral Spironolactone
How Does Spironolactone Treat Acne?
Spironolactone is an anti-androgen, meaning it blocks the effects of male hormones like testosterone and DHT on the skin. These androgens increase oil (sebum) production, leading to clogged pores and breakouts.
By lowering androgen activity, spironolactone reduces oil, inflammation, and hormonal breakouts—especially in adult women.
🧴 Topical Spironolactone: Targeted Treatment for Sensitive Skin
How it works: Applied directly to the skin, typically once or twice daily. It delivers anti-androgen effects exactly where you need them—without affecting the rest of your body.
Best for:
- Mild to moderate hormonal acne
- Sensitive to oral medications
- Concerned about systemic side effects
- Preferring a skincare-first approach
Pros:
- Localized treatment (minimal systemic absorption)
- Fewer side effects
- No lab monitoring required
- Easy to integrate into skincare routine
Cons:
- May take longer to see results
- Less effective for severe or cystic acne
👉 Get Topical Spironolactone from Oana Health
💊 Oral Spironolactone: Full-Body Hormonal Support
How it works: Taken as a daily pill, usually between 50–150mg. It lowers androgen levels systemically, which helps reduce acne from the inside out.
Best for:
- Moderate to severe hormonal acne
- Jawline and chin breakouts
- Oily skin and acne + facial hair or scalp thinning
- PCOS-related skin issues
Pros:
- Stronger and faster results
- Great for deep, cystic, or stubborn hormonal acne
- May also reduce facial hair and improve hair thinning
Cons:
- May cause side effects (like irregular periods, dizziness, or breast tenderness)
- Requires monitoring in some cases
- Not recommended during pregnancy
👉 Start Oral Spironolactone Treatment with Oana
Get Personalized Acne Care at Oana Health
At Oana Health, we treat hormonal acne with real medical care—not just surface-level products. Whether you’re looking for a low-commitment topical or stronger internal support, we’ve got you covered.
✅ Shop Topical Spironolactone
✅ Start Oral Spironolactone Care
✅ All online, fast, and affordable
