A prescription nasal spray that works on your brain's desire pathways — not your hormones. On-demand support for sexual desire and arousal, delivered to your door.
Bremelanotide activates the melanocortin receptors in your brain responsible for sexual motivation and desire. Unlike hormone therapies, it works through the nervous system — providing on-demand support when you want it, without affecting estrogen, progesterone, or testosterone levels.
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Bremelanotide targets the brain's desire pathways through a unique mechanism that no other treatment class addresses.
Bremelanotide binds to melanocortin-4 receptors (MC4R) in your brain — the same receptors that regulate motivation, appetite, and sexual interest. When activated, these receptors increase the brain's signaling for desire.
Use the nasal spray approximately 45-60 minutes before desired intimacy. Most women notice an increase in desire and arousal within this window. No daily pill, no buildup period — it works on-demand.
Once activated, the effects can persist for up to 12 hours or longer. You're not on a clock. The desire feels natural — not forced, not artificial — because it's your brain's own pathways responding.
Bremelanotide does not affect estrogen, progesterone, or testosterone levels. It works through the nervous system, not the endocrine system. No hormonal side effects and no interference with other hormonal treatments.
Bremelanotide works through a fundamentally different mechanism than anything else available.
HRT addresses estrogen and testosterone decline — but if your hormone levels are normal and desire is still low, hormones aren't the answer. Bremelanotide works on a completely different system.
Maca, ashwagandha, DHEA — these may support general wellness, but none have clinical evidence for directly increasing sexual desire. Bremelanotide is a prescription medication with clinical trial data.
Low desire isn't a stress problem you can breathe through. It's a neurological pattern. When the brain's desire pathways aren't activating, no amount of ambiance changes that. This medication targets those pathways directly.
Medications like sildenafil increase genital blood flow — but they don't increase desire. You can have physical arousal without wanting intimacy. Bremelanotide addresses the "wanting" part — desire and motivation, not mechanics.
Low sexual desire that causes distress has a clinical name: Hypoactive Sexual Desire Disorder (HSDD). It's more common than you think — and it's treatable. If prescribed.
“You deserve to feel like yourself again.”
Bremelanotide has been studied in clinical trials involving thousands of women and has a well-characterized safety and efficacy profile.
This is an on-demand treatment — use it only when you want support for intimacy. No daily dosing, no buildup required.
Administer one spray approximately 45-60 minutes before desired intimacy. The nasal spray format is quick, discreet, and easy to self-administer.
Do not exceed 1 dose in a 24-hour period. Your provider may recommend limiting use to no more than 8 doses per month.
Many women experience effects lasting up to 12 hours or more. There's no rush and no pressure — desire emerges naturally when the pathways are activated.
These typically resolve as your body adjusts. Taking an anti-nausea medication beforehand may help.
Not recommended for women with uncontrolled high blood pressure or significant cardiovascular disease. Tell your provider about all medications you take.
“I hadn't felt genuine desire in years. I thought it was just part of getting older. The nasal spray changed that — within an hour, I felt like myself again. Not like a different person, just like the version of me that actually wanted intimacy.”
“My doctor told me to try date nights and reduce stress. That wasn't the problem. This was the first time someone treated it like a real medical issue — because it is one. The nasal spray is easy to use and the difference is noticeable.”
Bremelanotide is a melanocortin receptor agonist — a prescription medication that activates the brain's desire pathways to increase sexual desire and arousal. It's the active ingredient in FDA-approved Vyleesi. Oana's Libido Enhancer delivers bremelanotide as a convenient nasal spray compounded by FDA-regulated pharmacies.
The nasal spray delivers the same active ingredient (bremelanotide) through a different route — no needles required. You simply administer one spray nasally, 45-60 minutes before desired intimacy. The nasal format is compounded by FDA-regulated pharmacies.
No. Bremelanotide works through the nervous system, not the endocrine system. It does not change estrogen, progesterone, or testosterone levels. It's safe to use alongside hormonal treatments like birth control or HRT — but always inform your provider of all medications you take.
Yes. Many women with PCOS experience low sexual desire as a symptom. Bremelanotide is compatible with common PCOS treatments like metformin, spironolactone, and tirzepatide. Discuss your full medication list during your health intake.
Most women notice an increase in desire and arousal within 30-60 minutes of use. Effects can last up to 12 hours or longer. Unlike daily medications that take weeks to build up, this is an on-demand treatment — it works when you use it.
Bremelanotide has been studied in clinical trials and has a well-characterized safety profile. The most common side effect is nausea, which typically lessens with repeated use. Your provider will monitor your response. It is not recommended for women with uncontrolled hypertension.
Yes. Bremelanotide is a prescription medication. Through Oana, you complete a 5-minute online health intake. A licensed physician reviews your information within 1-2 business days and, if appropriate, prescribes the treatment. It ships free to your door.
$149 for your first month, then $199/month. No insurance required. Free shipping included. FSA/HSA eligible. Cancel anytime.
Answer a few questions about your health history and symptoms. It takes less than 5 minutes and is completely private.
A licensed physician reviews your information and determines if this treatment is right for you.
If prescribed, your medication is compounded and shipped directly to you. Discreet packaging. Free shipping.
Complete a 5-minute online health intake. A licensed provider will review your information within 1-2 business days.
Get Started — $149 first monthFree shipping · Cancel anytime · If prescribedThe information provided on this page is for educational purposes only and is not intended as medical advice. Bremelanotide is the active ingredient in FDA-approved Vyleesi (injectable form). Oana's Libido Enhancer is a compounded nasal spray prepared by FDA-regulated pharmacies. Compounded medications are not FDA-approved. Individual results may vary. This product requires a prescription. A licensed physician will evaluate your health intake to determine if this treatment is appropriate for you. Do not use if you have uncontrolled high blood pressure or significant cardiovascular disease. Not for use during pregnancy or breastfeeding. If prescribed.