Custom compounded tretinoin for clogged pores, smoother texture, and clearer skin over time.
Tretinoin is one of the most studied prescription retinoids for acne. At Oana, we offer custom compounded tretinoin in 0.025%, 0.05%, and 0.1% strengths so your provider can match the formula to your skin goals, acne severity, and tolerance. It is compounded with niacinamide by default, and we can compound it without niacinamide if requested.
Get StartedThe Topical Spironolactone and Tretinoin Pack saves 20% automatically at checkout. Monthly plans ship a 20g bottle. Quarterly plans ship a 60g bottle and keep the same per-product pricing as Topical Spironolactone.
Tretinoin speeds up skin cell turnover, helping unclog pores before they become inflamed breakouts. It also supports smoother texture and can gradually fade the look of post-acne marks over time.
That makes it especially useful for stubborn comedonal acne, rough texture, and recurring hormonal breakouts. Because it can be irritating when you start, matching the strength to your skin matters. That is why Oana offers multiple strengths rather than a one-size-fits-all formula.
Start with custom tretinoin →Production medications for Oana currently support 0.025%, 0.05%, and 0.1% tretinoin strengths, and we can remove niacinamide if you need a simpler formula.
A lower starting strength for first-time retinoid users or more reactive skin.
A strong middle-ground option for ongoing acne control and smoother texture.
For patients who need a stronger formula and tolerate tretinoin well.
We can compound tretinoin without niacinamide when requested so your provider can tailor the formula to your skin.
Tretinoin helps clear pores and normalize turnover. Topical spironolactone helps calm androgen-driven oil production. Together, they create a stronger routine for patients dealing with recurring hormonal acne. When you bundle them in one checkout, you save 20% automatically.
Begin with a pea-sized amount at night every other evening unless your provider directs otherwise.
Cleanse gently, let your skin dry completely, then apply a thin layer over acne-prone areas.
Use a simple moisturizer to reduce dryness and help your skin acclimate.
Tretinoin makes skin more sun sensitive, so SPF every morning is essential.
Your provider can match the formula to your acne history, skin sensitivity, and treatment goals. Oana offers 0.025%, 0.05%, and 0.1% strengths so you are not locked into a single dose.
Yes. Tretinoin is compounded with niacinamide by default, but we can compound it without niacinamide if requested.
Yes. Many patients use tretinoin at night and topical spironolactone as part of the same acne routine. The duo can be started together through a single checkout flow.
Mild irritation can happen when starting tretinoin. Beginning slowly, moisturizing well, and adjusting the strength can help. If symptoms feel excessive, your provider can help tailor the formula or schedule.
No. Tretinoin is generally avoided during pregnancy. If you are pregnant, planning pregnancy, or breastfeeding, talk with your provider about safer alternatives.
Complete a quick online consultation and let your provider personalize the strength and formula for your skin.
Get Started — $59/monthFree shipping · Quarterly option available · Custom compounding available