Insulin Sensitizer
For insulin resistance, inflammation & PCOS
Topical metformin may improve insulin resistance and inflammation without the usual tummy troubles of oral metformin.
Starting at $59/month or $129/quarterly
Vanishing Cream
We use an oil-water vanishing cream specifically designed to deliver medications.
Science backed
Metformin takes sometime to build up in your body. Results should start after 3-4 weeks of daily application.

Testimonials
Relief for patients
Why our patients love topical metformin
"I’m so glad I discovered Oana’s metformin lotion! I used to struggle a lot with the side effects for oral metformin and this is a great alternative for me. I get the same benefits but no more upset stomach and nausea, and this helps me stick with it a lot more consistently."
Carrie S.
Topical Metformin
“It’s been a little over 5 weeks, and I’ve finally had my period after months! This has been such a relief for me. You really have to stick with it and be patient to notice results!”
Allison L.
Topical Metformin
Still thinking
about it?
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InSULIN SenSITIVTY
All insulin sensitizers
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$ 59
monthly
Metformin HCL Lotion 20%

$ 199
monthly
Oral Semaglutide GLP-1
Latest posts
From our blog
Read more about PCOS symptoms, latest research and treatments.
Top FDA Labeling Changes for Hormonal Medications
FDA removed black-box warnings from many menopausal hormone therapies, clarified dosing and local estrogen risks, and updated testosterone labels.
Spironolactone vs. Eflornithine: Drug Interactions
Compare spironolactone and topical eflornithine for hirsutism: interaction risks, monitoring needs, and safety considerations.
Pharmacological Options for PCOS Obesity
Overview of medication choices for PCOS-related obesity — metformin, GLP‑1 agonists, combination therapy, and alternatives, with benefits, risks, and costs.
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