Tirzepatide Injection
The most advanced treatment for PCOS insulin resistance and metabolic health. A weekly injection targeting both GLP-1 and GIP pathways — delivered to your door.
Free shipping · Cancel anytime · If prescribed
Licensed provider evaluates your health intake
Delivered to your door monthly
Targets both GLP-1 and GIP receptors
What Is Tirzepatide?
Tirzepatide is a dual-agonist medication that targets two key metabolic pathways: GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). By activating both receptors, it improves insulin sensitivity, reduces appetite, slows gastric emptying, and enhances fat metabolism — delivering broader metabolic benefits than medications that target only one pathway.
For women with PCOS, this dual action addresses the insulin resistance that drives many symptoms — weight gain, irregular periods, elevated androgens, acne, and unwanted hair growth. Clinical studies show tirzepatide produces significantly greater improvements in weight, insulin sensitivity, and hormonal balance compared to metformin or single-action GLP-1 medications.
Oana Health provides tirzepatide as a weekly subcutaneous injection — a simple once-weekly shot compounded by FDA-regulated pharmacies. 30-day supply delivered to your door.
Get Started — $199/moMechanism of Action
Activates Two Pathways
Unlike single-action medications, tirzepatide activates both GLP-1 and GIP receptors. This dual approach provides broader metabolic benefits than either pathway alone.
Improves Insulin Sensitivity
Reduces insulin resistance at the cellular level. For women with PCOS, this means lower insulin → lower androgens → fewer symptoms.
Reduces Appetite & Cravings
Signals your brain’s appetite centers to reduce hunger and cravings, especially for carbohydrates and sugar. Slows gastric emptying so you feel satisfied longer.
Supports Sustained Results
The combined metabolic effects support ongoing weight management and hormonal balance. Many women notice changes within 4–5 weeks of consistent use.
Tirzepatide vs Other PCOS Treatments
| Feature | Tirzepatide (Dual GLP-1/GIP) | Metformin ER | Single-Action GLP-1 |
|---|---|---|---|
| Mechanism | Dual GLP-1 + GIP agonist | Insulin sensitizer | GLP-1 agonist only |
| Weight management | Most significant in clinical trials | Modest | Significant |
| Insulin sensitivity | Superior improvement | Good improvement | Good improvement |
| Appetite reduction | Strong — dual pathway | Minimal | Moderate |
| GI side effects | Mild — GIP may reduce GI issues | Common (less with ER) | Common |
| Form | Weekly injection | Oral tablet (daily) | Varies |
| Price at Oana | $199/mo | $22/mo | $199/mo |
Not sure which is right for you? Complete our 5-minute health intake and your physician will recommend the best treatment for your pattern.
average weight loss in SURMOUNT clinical trials at the highest dose
is when many women begin noticing changes in appetite and energy
women studied across reproductive stages — consistent results regardless of age
What Women Are Saying
“I’ve always struggled with weight gain due to my PCOS. The Tirzepatide injection has helped me and also improved symptoms like irregular periods and acne!”
“It has helped me manage my weight and reduce some chin hairs I have had. The weekly injection is so much easier than I expected — just once a week and done.”
How to Take It
Choose Your Injection Site
Inject subcutaneously in the abdomen, thigh, or upper arm. Rotate injection sites each week to minimize irritation.
Inject Once Weekly
Administer one injection per week, on the same day each week. You can inject at any time of day, with or without food.
Simple & Quick
The injection takes less than a minute. Your Oana provider will walk you through the process and provide detailed instructions with your first shipment.
Stay Consistent
Most women begin noticing changes within 4–5 weeks. Full metabolic benefits develop over 3–6 months of consistent weekly use.
Safety Information
Common Side Effects
- Nausea (usually temporary)
- Decreased appetite
- Mild GI discomfort
- Headache
Less Common
- Diarrhea
- Constipation
- Fatigue
Important
Not recommended during pregnancy. Patients with a personal or family history of medullary thyroid carcinoma or MEN 2 syndrome should not use this medication. Tell your provider about all medications you take.
Also Available for PCOS
Frequently Asked Questions
Metformin improves insulin sensitivity through one pathway. Tirzepatide targets two pathways (GLP-1 and GIP), producing stronger effects on weight, appetite, and insulin resistance. Clinical trials show significantly greater improvements with tirzepatide compared to metformin alone.
Tirzepatide is a simple weekly subcutaneous injection — similar to an insulin pen. You inject once per week at home. Your Oana provider includes full instructions with your first shipment, and ongoing support is available.
Tirzepatide is the active ingredient in several brand-name medications. Oana’s injection is compounded by FDA-regulated pharmacies using the same active ingredient. Oana is not affiliated with Eli Lilly.
Your physician may recommend combining tirzepatide with spironolactone (for acne/hair symptoms) or eflornithine (for facial hair). Discuss your full medication list during your health intake.
Many women notice appetite changes and early improvements within 4–5 weeks. More significant metabolic results develop over 3–6 months of consistent use. Results vary by individual.
Many women start with metformin and upgrade to tirzepatide for stronger results. Your Oana physician can help transition your treatment plan.
Clinical trials tracked patients for up to 88 weeks with a consistent safety profile. A study of 2,542 women showed consistent effectiveness across all reproductive stages. Your provider monitors your progress and adjusts as needed.
No. Tirzepatide through Oana is $199 for a 30-day supply with no insurance required. Free shipping is included. FSA/HSA funds may be used.
Start Your Tirzepatide Treatment
Complete a 5-minute online health intake. A licensed provider will review your information within 1–2 business days.
Get Started — $199/monthResults may vary. Tirzepatide contains the same active ingredient as FDA-approved injectable tirzepatide, compounded by FDA-regulated pharmacies. Oana is not affiliated with Eli Lilly. If prescribed. Always use “health intake” — never “consultation.” Patients with a personal or family history of medullary thyroid carcinoma or MEN 2 syndrome should not use this medication.